Jennifer McClure, PhD, is director of Investigative Science at Kaiser Permanente Washington Health Research Institute (KPWHRI). She is also a senior investigator and clinical psychologist whose research focuses on developing new interventions to reduce people’s risk of chronic disease and cancer or help them better manage existing chronic disease through:
Much of Dr. McClure’s research emphasizes creating highly individualized behavioral treatments that can be disseminated on a population level, through health care systems and tobacco quitlines or directly to individuals via digital health tools, such as mobile health (mHealth) apps. Her goal is to design programs that are effective, convenient, engaging, and cost-effective, understanding that to make the leap from research to real world, interventions should meet these criteria.
Dr. McClure is best known for her research creating novel treatments for nicotine dependence, particularly interventions targeted to smokers who are ambivalent about quitting. These individuals may want to quit smoking some day, but are not yet ready to give up tobacco. Most smokers fall into this category, but few interventions are targeted to this important group. Her research has demonstrated the effectiveness of using proactive counseling and online interventions to motivate and support smoking cessation among ambivalent smokers. Her work has also shed light on the potential risks and benefits of using biological indicators of disease or disease risk to motivate quitting. Now she is developing two new mHealth apps to help ambivalent smokers kick the habit: one designed for anyone who smokes and one designed specifically for smokers living with HIV.
Dr. McClure’s collaborative research covers a range of topics from reducing sedentary behavior to comparing the effectiveness of various strategies for assessing and diagnosing high blood pressure.
In recognition of her scientific contributions, Dr. McClure was named a fellow in the Society of Behavioral Medicine (SBM) in 2013 and a fellow in the Society for Research on Nicotine and Tobacco in 2018. In 2019 she joined the faculty of the Kaiser Permanente Bernard J Tyson School of Medicine as a professor in Health Systems Science. Dr. McClure is also an affiliate professor of health services at the University of Washington School of Public Health and an affiliate investigator in the Division of Public Health Sciences at the Fred Hutchinson Cancer Research Center. She currently serves as the Secretary and Treasurer of the Society for Research on Nicotine and Tobacco.
Tobacco cessation; pharmocogenomics of nicotine addiction; treatment adherence; population-based behavior interventions; health risk communications; oral health promotion; dietary change; physical activity promotion; informed decision-making; psychoneuroimmunology; HIV
Development of eHealth and mHealth intervention tools
Depression treatment and development of behavior change interventions for people with serious mental illness
Prevention and treatment
McClure JB, Curry SJ, Cofta-Gunn L, Wetter D. Negative affect, depression history, and smoking relapse. Ann Behav Med. 2001;23:S156.
Cinciripini PM, McClure JB, Wetter DW, Perry J, Blalock JA, Cinciripini LG, Friedman KE, Skaar K. An evaluation of videotaped vignettes for smoking cessation and relapse prevention during pregnancy: the Very Important Pregnant Smokers (VIPS) program. Tob Control. 2000;9 Suppl 3():iii61-3. PubMed
Catz SL, McClure JB, Jones GN, Brantley PJ. Predictors of outpatient medical appointment attendance among persons with HIV. AIDS Care. 1999;11(3):361-73. PubMed
Wetter DW, Fiore MC, Young TB, McClure JB, de Moor CA, Baker TB. Gender differences in response to nicotine replacement therapy: objective and subjective indices of tobacco withdrawal. Exp Clin Psychopharmacol. 1999;7(2):135-44. PubMed
McClure JB, Catz SL, Brantley PJ. Early appointment adherence among persons living with HIV. AIDS and Behavior. 1999;3(2):157-165.
McClure JB, Wetter DW, deMoor C, Cinciripini PN, Carmack CL, Gritz ER. Alcohol use and tobacco abstinence. Ann Behav Med. 1999;21:S162.
Wetter DW, McClure JB. Smoking cessation: research and clinical strategies. Highlights in Oncology Practice. 1999;16(4):86-90.
McClure JB. Abstinence rates achieved with buproprion corrected. Oncology (Huntingt). 1998;12(9):1303. PubMed
Cinciripini PM, McClure JB. Smoking cessation: recent developments in behavioral and pharmacologic interventions. Oncology (Huntingt). 1998;12(2):249-56, 259; discussion 260, 265, .,. PubMed
Catz SL, McClure JB, Jones GN, Brantley PJ. Factors associated with HIV outpatient nonadherence. Ann Behav Med. 1998;20 (Suppl):S49.
Research led by KPWHRI’s Beverly Green, MD, MPH, finds that patients prefer at-home monitoring of blood pressure.
Dr. Jennifer McClure shares advice and resources for staying physically and emotionally well during the COVID-19 crisis, and beyond.
As Dr. Jennifer McClure completes the last of three innovative studies, she reflects on how the work began, the difference it may make, and what happens next.
Tobacco remains a public health priority. Dr. Jennifer McClure discusses her new findings comparing ’acceptance and commitment therapy’ to standard care.