Jennifer McClure, PhD, is director of Investigative Science at Kaiser Permanente Washington Health Research Institute (KPWHRI). She is also a senior investigator and clinical psychologist whose research focuses on developing new interventions to reduce people’s risk of chronic disease and cancer or help them better manage existing chronic disease through:
Much of Dr. McClure’s research emphasizes creating highly individualized behavioral treatments that can be disseminated on a population level, through health care systems and tobacco quitlines or directly to individuals via digital health tools, such as mobile health (mHealth) apps. Her goal is to design programs that are effective, convenient, engaging, and cost-effective, understanding that to make the leap from research to real world, interventions should meet these criteria.
Dr. McClure is best known for her research creating novel treatments for nicotine dependence, particularly interventions targeted to smokers who are ambivalent about quitting. These individuals may want to quit smoking some day, but are not yet ready to give up tobacco. Most smokers fall into this category, but few interventions are targeted to this important group. Her research has demonstrated the effectiveness of using proactive counseling and online interventions to motivate and support smoking cessation among ambivalent smokers. Her work has also shed light on the potential risks and benefits of using biological indicators of disease or disease risk to motivate quitting. Now she is developing two new mHealth apps to help ambivalent smokers kick the habit: one designed for anyone who smokes and one designed specifically for smokers living with HIV.
Dr. McClure’s collaborative research covers a range of topics from reducing sedentary behavior to comparing the effectiveness of various strategies for assessing and diagnosing high blood pressure.
In recognition of her scientific contributions, Dr. McClure was named a fellow in the Society of Behavioral Medicine (SBM) in 2013 and a fellow in the Society for Research on Nicotine and Tobacco in 2018. In 2019 she joined the faculty of the Kaiser Permanente Bernard J Tyson School of Medicine as a professor in Health Systems Science. Dr. McClure is also an affiliate professor of health services at the University of Washington School of Public Health and an affiliate investigator in the Division of Public Health Sciences at the Fred Hutchinson Cancer Research Center. She currently serves as the Secretary and Treasurer of the Society for Research on Nicotine and Tobacco.
Tobacco cessation; pharmocogenomics of nicotine addiction; treatment adherence; population-based behavior interventions; health risk communications; oral health promotion; dietary change; physical activity promotion; informed decision-making; psychoneuroimmunology; HIV
Development of eHealth and mHealth intervention tools
Depression treatment and development of behavior change interventions for people with serious mental illness
Prevention and treatment
McClure JB, Jack L, Deprey M, Catz S, McAfee T, Zbikowski S, Westbrook E, Swan G. Canary in a coal mine? Interest in bupropion SR use among smokers in the COMPASS trial. Nicotine Tob Res. 2008;10(12):1815-6. PubMed
Halperin AC, McAfee TA, Jack LM, Catz SL, McClure JB, Deprey TM, Richards J, Zbikowski SM, Swan GE. Impact of symptoms experienced by varenicline users on tobacco treatment in a real world setting. J Subst Abuse Treat. 2009 Jun;36(4):428-34. Epub 2008 Nov 11. PubMed
Bush TM, McAfee T, Deprey M, Mahoney L, Fellows JL, McClure J, Cushing C. The impact of a free nicotine patch starter kit on quit rates in a state quit line. Nicotine Tob Res. 2008;10(9):1511-6. PubMed
Curry SJ, Wetter DW, Grothaus LC, McClure JB, Taplin SH. Designing and evaluating individual-level interventions for cancer prevention and control. In SM Miller, DJ Bowen, RT Croyle, J Rowland (Eds.). Handbook of Behavioral Science and Cancer. Washington DC: American Psychological Association; 2008.
McAfee TA, Bush T, Deprey TM, Mahoney LD, Zbikowski SM, Fellows JL, McClure JB. Nicotine patches and uninsured quitline callers. A randomized trial of two versus eight weeks. Am J Prev Med. 2008;35(2):103-10. PubMed
Zikmund-Fisher BJ, Ubel PA, Smith DM, Derry HA, McClure JB, Stark A, Pitsch R, Fagerlin A. Communicating side effect risks in a tamoxifen prophylaxis decision aid: the debiasing influence of pictographs. Patient Educ Couns. 2008;73(2):209-14. Epub 2008 Jul 2. PubMed
Strecher VJ, McClure JB, Alexander GL, Chakraborty B, Nair VN, Konkel JM, Greene SM, Collins LM, Carlier CC, Wiese CJ, Little RJ, Pomerleau CS, Pomerleau OF. Web-based smoking-cessation programs: results of a randomized trial. Am J Prev Med. 2008;34(5):373-81. PubMed
Alexander GL, Divine GW, Couper MP, McClure JB, Stopponi MA, Fortman KK, Tolsma DD, Strecher VJ, Johnson CC. Effect of incentives and mailing features on online health program enrollment. Am J Prev Med. 2008;34(5):382-8. PubMed
Strecher VJ, McClure J, Alexander G, Chakraborty B, Nair V, Konkel J, Greene S, Couper M, Carlier C, Wiese C, Little R, Pomerleau C, Pomerleau O. The role of engagement in a tailored web-based smoking cessation program: randomized controlled trial. J Med Internet Res. 2008;10(5):e36. PubMed
Swan GE, Jack LM, Javitz HS, McAfee T, McClure JB. Predictors of 12-month outcome in smokers who received bupropion sustained-release for smoking cessation. CNS Drugs. 2008;22(3):239-56. PubMed
Research led by KPWHRI’s Beverly Green, MD, MPH, finds that patients prefer at-home monitoring of blood pressure.
Dr. Jennifer McClure shares advice and resources for staying physically and emotionally well during the COVID-19 crisis, and beyond.
As Dr. Jennifer McClure completes the last of three innovative studies, she reflects on how the work began, the difference it may make, and what happens next.
Tobacco remains a public health priority. Dr. Jennifer McClure discusses her new findings comparing ’acceptance and commitment therapy’ to standard care.